Aniracetam

Aniracetam is a nootropic that is in the racetam family.  It is generally considered to be more potent than Piracetam.  First synthesized by chemist Hoffmann La-Roche in the 1970’s, Aniracetam is used as a prescription nootropic in Europe.  It is sold as a dietary supplement in the United States.

What separates Aniracetam from many of the other nootropics is its effectiveness as an anxiolytic (anxiety reducer).  It is said to reduce anxiety without causing fatigue and loss of motivation like most prescription anxiolytics do.  Like all the nootropics, Aniracetam has also been shown to improve learning and memory.

aniracetam

What are some of the benefits of Aniracetam?

  • ⇒ Reduced Anxiety
  • ⇒ Improved Concentration
  • ⇒ Enhanced Memory
  • ⇒ Heightened Reflexes
  • ⇒ Improvement in Mood/Decreased Depression
  • ⇒ General Cognitive Enhancement

 

How does it work?Aniracetam

Like all nootropics, the exact mechanism by which Aniracetam works is not totally understood.  However, it is believed to work like the other racetams.  Aniracetam stimulates the AMPA receptor site specifically, which is known to play a role in memory and learning[1].  The anxiolytic effects of Aniracetam are thought to be due, at least in part, to its ability to activate dopamine receptors[2].  This explains how it is able to reduce anxiety without causing sedation and drowsiness.

Safety/Side Effects

Aniracetam has been shown to be generally safe when taken at recommended dosages.  Side effects are rare and are usually only seen when taken at high doses for prolonged periods of time.  Tolerance to Aniracetam has been observed but can be avoided by using it infrequently or cycling its use.  Occasional side effects may include headache, nausea, upset stomach, and insomnia.  If you experience any of these side effects, discontinue use and consult a doctor.  As with all supplements, you should always consult a physician before starting anything new.

Dosage

The recommended dosage of Aniracetam is 1-2 grams.  It is always a good idea to start at the lowest dose and work your way up.  Some people report the desired effects with just 1 gram.  Others need the maximum recommended dose of 2 grams to experience the full cognitive and anxiolytic effects.

 

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Notes

[1]  Ito et al.; Tanabe, S; Kohda, A; Sugiyama, H (1990). “Allosteric potentiation of quisqualate receptors by a nootropic drug aniracetam”J. Physiol. 424: 533–543.

[2]  Nakamura K; Kurasawa M (May 2001). “Anxiolytic effects of aniracetam in three different mouse models of anxiety and the underlying mechanism”. Eur J Pharmacol. (Kanagawa, Japan). 420 (1): 33–43.