Of all the wonderful plants and herbs that have cognition-enhancing and mood-boosting properties, few of them are more popular than ginkgo biloba. It's been around for centuries and has a long history of being used to treat memory problems, blood disorders, and other illnesses. In recent years, ginkgo biloba has been used for its cognition-boosting and memory-enhancing effects.
Ginkgo biloba, often simply referred to as ginkgo, is the most commonly used supplement for brain health.1 It's been used for thousands of years all over the world to treat a number of conditions.2 The scientific community has taken an interest in ginkgo and recent studies have started to shed some light onto how this fascinating herb works.
We'll look at the benefits, potential negative effects, dosage, and where to buy ginkgo biloba shortly. First, lets examine what exactly ginkgo is.
What is Ginkgo Biloba?
Ginkgo biloba, often simply referred to as ginkgo (sometimes spelled gingko) and also known as the maidenhair tree, is one of the oldest species of trees on the planet.3 It has a long history of use in traditional Chinese medicine and has been used for its health benefits by many other cultures.
Some of the conditions that ginkgo has historically been used for include dementia, anxiety, glaucoma, macular degeneration, premenstrual syndrome, intermittent claudication, Alzheimer's disease, cognitive decline, high blood pressure, altitude sickness, tinnitus, and peripheral artery disease45. As more and more scientific studies are done on ginkgo, its effectiveness at treating some of these conditions is being rigorously explored.
In recent years, ginkgo biloba extract has been consumed for its nootropic benefits. Users report improved memory, reduced anxiety, increased reaction time, improved blood flow, and general cognitive enhancement, among other benefits. Let's take a detailed look at some of these benefits and the science to support them.
Ginkgo Biloba Benefits
Ginkgo users have reported a variety of cognitive and physical benefits from taking the plant. Some of these benefits are backed by scientific studies, while others are not. Here are some of the ginkgo biloba benefits that have been studied.
Improved Memory – This is one of the most common reasons that people use ginkgo. But is the claim that ginkgo biloba can improve memory backed by science? The answer is a resounding yes! There have been several studies that have proven ginkgo to be a powerful memory enhancer.
In one study, researchers gave healthy adults 240 mg of a ginkgo extract daily for six weeks. After taking the ginkgo extract, the participants were able to remember more things and remember things clearer.6
In another study, researchers looked at what effects ginkgo had after just a single dose. They gave some participants only the ginkgo biloba extract, others only a ginseng extract, some received both, and others a placebo. The participants in the ginkgo, ginseng, and ginkgo/ginseng groups showed improvements in memory performance, in addition to improved math performance. The participants in the ginkgo only group also showed an improvement in mood.7
These are just two examples, but there are at least a dozen other studies that also demonstrate ginkgo biloba's ability to improve memory.1 This may be ginkgo's most well-known benefit, but there are several others.
Reduced Stress and Anxiety – Users typically don't use ginkgo for its anxiety-reducing effects, but it can be a nice additional benefit. Some people who supplement with ginkgo extract report reduced anxiety and stress, which has been noticed in a couple different studies.
In one study, participants with anxiety were given either 480 mg of ginkgo extract, 240 mg, or a placebo for four weeks. Their anxiety levels were checked throughout the study and those who received the high dose of ginkgo showed the greatest improvement. The low dose group also improved, but not by quite as much. And while there was improvement in the placebo group, it was significantly less than in the groups receiving the ginkgo biloba extract.8
In another study of healthy volunteers, the effects of ginkgo on stress were examined. A single dose of 120 mg of ginkgo biloba extract was shown to improve acute stress reaction, by preventing blood pressure and cortisol levels from rising.9
Slowed Cognitive Decline – There have been well over a dozen scientific studies that have examined the effect that ginkgo has on slowing cognitive decline in the elderly and the results have all been very positive.
One randomized, double-blind, placebo-controlled study (the standard for studying medicine) took patients with Alzheimer's disease or vascular dementia and gave them either a ginkgo extract or a placebo for 22 weeks. After that time, the participants were assessed using several different tests. Those in the ginkgo group showed significant improvements in cognition. The study also noted that the participants in the ginkgo group had no more side effects than the placebo group.10
These are just three potential ginkgo biloba benefits that have been studied. Research indicates that it may also be useful for people with glaucoma, intermittent claudication, macular degeneration, and other conditions. Now, let's look at the potential negative effects of ginkgo.
Potential Ginkgo Biloba Negative Effects
Ginkgo is generally very well-tolerated. Most people who take it do not experience any negative effects. However, unwanted effects from taking ginkgo biloba are possible just like with anything else you put in your body.
Some of the most commonly reported negative effects of taking ginkgo include upset stomach, headache, dizziness, and skin reactions.5 These unwanted effects are usually mild and go away shortly after discontinuing ginkgo.
Ginkgo may increase the risk for internal bleeding. There have been reports of ginkgo and internal bleeding but it's not clear what role it played, if any. If you are taking blood thinners like Coumadin (warfarin sodium), Eliquis (apixaban), Pradaxa (dabigatran), or others, you may want to use extra caution when using ginkgo. However, ginkgo has been shown to have no effect on INR (International Normalized Ratio) in people taking warfarin.11
If you are taking prescription antidepressants, especially MAOIs, it is especially important that you talk to you doctor before taking ginkgo. If you have seizures, ginkgo may not be right for you, as it may make you more likely to have one. And lastly, you should not take ginkgo if you are pregnant or plan on becoming pregnant.
As always, talk to a licensed healthcare professional before starting or stopping any new supplement, medication, exercise program, or behavioral routine. Most doctors aren't knowledgeable about nootropics, so you might have to educate yours a bit. The References section toward the bottom of this page is a good place to start.
How To Take Ginkgo Biloba
There are no official guidelines for taking ginkgo biloba. However, between clinical studies and anecdotal reports, we can look at what seems to work for most people.
Studies have used dosages ranging from 120 milligrams (mg) a day and up. In the studies that compared the effectiveness of more than one dosage, the higher dosage usually showed greater results. A lot of users report that they get the best results from a dosage of around 500 mg per day, either once a day or divided into two doses. However, many people notice the benefits of ginkgo biloba with as little as 120 mg a day.
Ginkgo extract can be taken with or without food. It may be slightly more effective if taken on an empty stomach. However, this can cause upset stomach in some people. If this happens to you, try taking ginkgo with a small meal. Most users like to take it early in the day.
As with all supplements, you should consult with your doctor before taking ginkgo biloba. Though ginkgo seems to be very safe for most people, it's always a good idea to talk with a licensed physician before taking anything new.
Where To Buy Ginkgo Biloba
Ginkgo is one of the most common nootropics and can be found in a variety of places. It's often carried by supplement shops like Vitamin World, GNC, and others. Ginkgo can also be found in pharmacies and large department stores like Walmart and Target. And, of course, it can be found from a variety of retailers online, including Amazon.
While there are a number of places to buy ginkgo biloba extract online, I recommend Pure Nootropics. I've been ordering from them for years and their products are always of the highest quality. Unfortunately, there are some shady supplement manufacturers out there and you should be wary of companies that don't have a proven track records. Pure Nootropics does. They've been around for years, have excellent products, reasonable prices, fast shipping, and top-notch customer service.
That being said, there's no shortage of trustworthy places to buy ginkgo biloba online. To see an up-to-date list of nootropic vendors you can trust, check out this article about Where To Buy Nootropics.
Conclusion
As you can see, ginkgo biloba offers a number of potential nootropic benefits. While ginkgo can often be effective on its own, it can also make a great addition to a nootropic stack.
Ginkgo use has been extensively studied and shown that it can have a beneficial effect on memory, anxiety levels, and more. Not only has gingko been shown to be very safe for most people, it's also readily available and very affordable.
Have you tried ginkgo biloba? What has your experience with it been like? Please leave your answer in the comments section at the bottom. If you're interested in learning about other memory-boosting nootropics, you may want to check out The Best Nootropics For Memory. And if you haven't already, sign up for the Nootropics Zone newsletter below to learn about dozens of different brain-boosting substances.
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References
1Ginkgo biloba. (n.d.). From Examine.com. Retrieved January 26, 2024 from https://examine.com/supplements/ginkgo-biloba/
2Michel, P.F., & D. Hosford. 1988. Ginkgo biloba: from “living fossil” to modern therapeutic agent. In Gmkgohdes 2014 Chemistry, Biology, Pharmacology, and Clmlcal Perspectives, vol. 1, P. Braquet (ed.), pp 1-8. J. R. Prous, Barcelona.
3Ginkgo biloba. (n.d.). Natural Resources Conservation Service PLANTS database. USDA. Retrieved January 26, 2024 from https://plants.usda.gov/core/profile?symbol=GIBI2
4Ginkgo biloba. (n.d.). From Wikipedia.com. Retrieved November 9, 2016 from https://en.wikipedia.org/wiki/Ginkgo_biloba
5Ginkgo biloba. (n.d.). From University of Maryland Medical Center. Retrieved November 9, 2016 from http://umm.edu/health/medical/altmed/herb/ginkgo-biloba
6Kaschel, R. (2011). Specific memory effects of Ginkgo biloba extract EGb 761 in middle-aged healthy volunteers. Phytomedicine. 18(14):1202-7.
7Kennedy, D.O., Scholey, A.B., & Wesnes, K.A. (2002). Modulation of cognition and mood following administration of single doses of Ginkgo biloba, ginseng, and ginkgo/ginseng combination to healthy young adults. Physiology & Behavior. 15(75):739-51.
8Woelk, H., Arnoldt, K.H., Kieser, M., & Hoerr, R. (2007). Ginkgo biloba special extract EGb 761 in generalized anxiety disorder and adjustment disorder with anxious mood: a randomized, double-blind, placebo-controlled trial. Journal of Psychiatric Research. 41(6):472-80.
9Jezova, D., Duncko, R., Lassanova, M., Kriska, M., & Moncek, F. (2002). Reduction of rise in blood pressure and cortisol release during stress by Ginkgo biloba extract (EGb 761) in healthy volunteers. Journal of Physiology and Pharmacology. 53(3):337-48.
10Napryeyenko, O., Borzenko, I., & GINDEM-NP Study Group. (2007). Ginkgo biloba special extract in dementia with neuropsychiatric features. A randomized, placebo-controlled, double-blind clinical trial. Arzneimittelforschung. 57(1):4-11.
11Jiang, X., Williams, K.M., Liauw, W.S., Ammit, A.J., Roufogalis, B.D., Duke, C.C., Day, R.O., & McLachlan, A.J. (2005). Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects. British Journal of Clinical Pharmacology. 59(4):425-32.
[This article was originally published on November 11, 2016. Updated January 26, 2024.]
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