Peanut butter and jelly. Salt and pepper. Spaghetti and meatballs. L-theanine and caffeine.
Some things just work incredibly well together. This is absolutely true of L-theanine and caffeine. This powerful combo is a great nootropic mini-stack.
We all know that caffeine can give us a boost in mood, focus, and wakefulness. But it often comes at a cost. Some people experience caffeine jitters and a big crash a few hours after consumption. By combining caffeine with L-theanine, you can potentially eliminate the jitters and crash completely.
In this article, we're going to discuss this safe-and-effective, tried-and-true nootropic stack. Let's start by taking a quick look at what L-theanine and caffeine are.
What Is L-Theanine?
Just about everyone knows what caffeine is. There's a good chance you've got some flowing through your system right now. But L-theanine isn't nearly as well known as caffeine. So what is it?
L-theanine (often just called theanine) is a non-essential amino acid that is found naturally in green tea.1 It's no secret that green tea is good for you and L-theanine is part of the reason why. Unfortunately, you'd have to drink tons of green tea to get the enough L-theanine to notice its calming effect. One cup only contains about 20 milligrams.2 But you can experience this and other L-theanine benefits by taking it in supplement form.
Several scientific studies have shown that L-theanine is able to reduce anxiety. If you'd like to learn more about L-theanine and really dive into the science behind it, check out this article: L-Theanine – A Calming Nootropic.
But L-theanine doesn't just reduce anxiety. For most people, it reduces anxiety without causing sedation. Prescription anxiolytics (anxiety reducers) definitely work but often leave you feeling like a zombie. L-theanine has been shown to be as effective at reducing anxiety as some prescription anxiolytics but without being as sedating.3
Decreased anxiety is only one of L-theanine's benefits. Let's take a look at some of the others.
Benefits Of L-Theanine
In addition to being a potent anxiety reducer, L-theanine has also been shown to improve sleep quality.4 And when taken in combination with caffeine, it has been shown to even improve mood.5 Here are some of the main benefits of L-theanine by itself:
- Decreased anxiety
- Decreased physical and mental stress
- Improved sleep quality
- Increased relaxation
What Is Caffeine?
I won't say very much about caffeine because you probably know all about it already. Like I said earlier, there's a good chance you've got some in your system as you read this. More than half of all Americans consume caffeine daily.6 Worldwide, caffeine is the most-commonly-used psychoactive substance, even more than alcohol.7
There's a reason why so many people consume caffeine: it's generally safe and unquestionably effective. Caffeine is a central nervous system (CNS) stimulant that increases wakefulness by affecting the compound adenosine in the brain.8 Users find that it helps them to stay awake, stay focused, and be more productive.
Unfortunately, a lot of caffeine users also find that it increases anxiety, causes jitters, and makes it harder to fall asleep. And a few hours after consumption, a lot of users report the dreaded crash when the caffeine wears off and their energy levels plummet.
Fortunately, these potential negative effects of caffeine can be reduced or eliminated entirely by consuming it with L-theanine. Let's briefly look at the benefits of caffeine by itself. Then we'll explore the magic of consuming L-theanine and caffeine together.
Benefits Of Caffeine
Caffeine has a lot of potential benefits. Here are some of its well-known benefits that have been scientifically established:
- Reduced fatigue and drowsiness
- Increased wakefulness
- Improved reaction time and motor coordination
- Improved focus and concentration9
- Increased physical performance10
- Increased productivity
L-Theanine And Caffeine Stack
If you're not familiar with the term stack, it simply means taking two-or-more nootropics together to increase their effectiveness. The combination of L-theanine and caffeine together is one of the simplest, safest, and most-effective nootropic stacks being used around the world today. This magic combo provides all the benefits of caffeine without many of its negative effects.
Users of this stack, myself included, find that it creates a state of calm focus. I get the wakefulness and increased productivity from the caffeine without the anxiety, crash, and insomnia that usually go along with it. But it's not just me: countless others who've used this stack have reported the same benefits. And there is plenty of science to back up these claims.
A 2017 review looked at the effect that the constituents of green tea (caffeine, l-theanine, and EGCG) had on mood and cognition.11 This review looked at 49 human studies that had previously been conducted. The researchers concluded that L-theanine and caffeine “have clear beneficial effects on sustained attention, memory, and suppression of distraction.” In other words, L-theanine and caffeine clearly have a nootropic effect.
Another review published nearly a decade earlier in the scientific journal Biological Psychology looked at the psychological effects of L-theanine, caffeine, and the two together.12 This review found that L-theanine and caffeine together reduced mental fatigue, decreased headaches, increased wakefulness and alertness, and improved several aspects of memory and attention. The researchers also briefly discussed mechanisms of action, noting that both L-theanine and caffeine affect the neurotransmitters dopamine, serotonin, glutamate, and gamma-aminobutyric acid (GABA).
As far as nootropic stacks go, it doesn't get any simpler than this one. And there are plenty of scientific studies to support its safety and effectiveness. Let's briefly review the benefits of the caffeine-and-L-theanine stack.
Benefits Of The Caffeine And L-Theanine Stack
Here are some of the reported benefits of taking L-theanine and caffeine together:
- Increased focus
- Increased wakefulness and alertness
- Reduced fatigue and tiredness
- Improved memory and concentration
- Increased productivity
- Creates a state of calm focus
- Increased energy
- Improved physical and sports performance13
L-Theanine and Caffeine Safety
L-theanine has a great safety profile. In fact, the Food & Drug Administration (FDA) has given it the rating of GRAS or generally recognized as safe.1 And studies show that it's incredibly safe even at extremely high doses.14 However, some people may experience mild, unwanted effects from L-theanine. These rare negative effects can include headache, dizziness, gastrointestinal discomfort, nausea, and low blood pressure.15
Like L-theanine, the FDA has also given caffeine the designation GRAS.16 When taken in reasonable amounts, caffeine is generally very safe. However, extremely high doses of caffeine can be lethal.17 And caffeine can have a number of potential negative effects. These include anxiety, insomnia, jitters, upset stomach, nausea, loss of appetite, and others.
When taken together, especially at recommended dosages, L-theanine and caffeine seem to be extremely safe. L-theanine may even reduce some of the negative effects of caffeine like increased blood pressure.18
Caffeine & L-Theanine Dosage
A wide range of dosages have been used in the dozens of studies done on L-theanine and caffeine. Depending on the study, participants were given anywhere from 50-2,000 milligrams (mg) of L-theanine and anywhere from 50-400 mg of caffeine. Within these ranges, the researchers found no serious negative effects.
For nootropic purposes, most users take anywhere from 100-400 mg of L-theanine and 50-200 mg of caffeine. Some people like a theanine-to-caffeine ratio of 2:1. In other words, twice as much L-theanine as caffeine. Others find a 1:1 ratio to work best.
As always, you want to start low and work your way up as needed. If you don't regularly consume caffeine, you may have great results with as little as 50 mg of caffeine and 100 mg of L-theanine. However, you may need a higher dosage if you're a regular caffeine consumer like me. To notice the benefits of L-theanine and caffeine, I need to take at least 200 mg of each. Sometimes I'll go as high as 400 mg of each but never higher than that in a 24-hour period.
Before starting any new supplements, diets, workout programs, or behavioral routines, it's always a good idea to consult a licensed healthcare professional. This is especially important if you are currently taking any prescription medications. Most doctors don't know very much about nootropics so you might have to educate yours a bit. The References section at the bottom of this page is a good place to start.
Where To Buy L-Theanine & Caffeine
Both L-theanine and caffeine are incredibly common and easy to find. They can often be found in stores that sell health supplements. You can also find them on Amazon.
For experienced nootropic users who prefer powders to pills and capsules, you can find both L-theanine and caffeine in powder form at Pure Rawz. By using nootropic powders, you can really dial in your dosage and figure out your perfect L-theanine to caffeine ratio. Pure Rawz has an awesome selection of high-quality products, reasonable prices, and discreet shipping. If you're looking for a particular nootropic, there's a good chance Pure Rawz carries it. Go check out their massive selection of nootropics and other products. And you can save 10% on every order by using the coupon code nz10.
Conclusion
If you're looking for a simple, safe, and effective nootropic stack, you've found it. As we've seen, L-theanine and caffeine is the perfect nootropic combo. People from around the world use it to increase wakefulness, focus, attention, and overall productivity without causing jitters, anxiety, and the dreaded caffeine crash. And there's no shortage of science to support both the safety and effectiveness of the caffeine and L-theanine stack.
Have you used L-theanine and caffeine together? What has your experience been like? Please leave your answer in the comments section at the bottom. And if you haven't already, please join the Nootropics Zone mailing list below to learn about dozens of productivity-boosting supplements.
To learn more about nootropics, sign up for the Nootropics Zone newsletter. You'll get the free gift, The Ultimate Nootropics Quick Reference Guide.
References
1Theanine. (n.d.). Wikipedia. Retrieved May 3, 2024 from https://en.wikipedia.org/wiki/Theanine
2Boros, K., Jedlinszki, N., & Csupor, D. (2016). Theanine and caffeine content of infusions prepared from commercial tea samples. Pharmacognosy Magazine, 12(45):75-9.
3Lu, K., Gray, M., Oliver, C., Liley, D., Harrison, B., et al. (2004). The acute effects of l-theanine in comparison with alprazolam on anticipatory anxiety in humans. Human Psychopharmacology, 19:457-65.
4Kim, S., Jo, K., Hong, K., Han, S., & Suh, H. (2019). GABA and l-theanine mixture decreases sleep latency and improves NREM sleep. Pharmaceutical Biology, 57(1):65-73.
5Dodd, F., Kennedy, D., Riby, L, & Haskell-Ramsay, C. (2015). A double-blind, placebo-controlled study evaluating the effects of caffeine and l-theanine both alone and in combination on cerebral blood flow, cognition, and mood. Psychopharmacology, 232(14):2563-76.
6Gaille, B. (2017, May 25). 51 dramatic caffeine consumption statistics. Retrieved May 3, 2024 from https://brandongaille.com/50-dramatic-caffeine-consumption-statistics/
7Majithia, N. (2007, Nov. 10). Caffeine: understanding the world's most popular psychoactive drug. Journal of Young Investigators. Retrieved October 2, 2020 from https://www.jyi.org/2007-november/2007/11/10/caffeine-understanding-the-worlds-most-popular-psychoactive-drug
8Nehlig, A., Daval, J., & Debry, G. (1992). Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic, and psychostimulant effects. Brain Research Reviews, 17(2):139-70.
9Nehlig, A. (2010). Is caffeine a cognitive enhancer? Journal of Alzheimer's Disease, 20:S85-94.
10Burke, L. (2008). Caffeine and sports performance. Applied Physiology, Nutrition, and Metabolism, 33(6):1319-34.
11Dietz, C., & Dekker, M. (2017). Effect of green tea phytochemicals on mood and cognition. Current Pharmaceutical Design, 23(19):2876-2905.
12Haskell, C., Kennedy, D., Milne, A., Wesnes, K., & Scholey, A. (2008). The effects of l-theanine, caffeine and their combination on cognition and mood. Biological Psychology, 77(2):113-22.
13Zaragoza, J., Tinsley, G., Urbina, S., Villa, K., Santos, E., et al. (2019). Effects of acute caffeine, theanine, and tyrosine supplementation on mental and physical performance in athletes. Journal of the International Society of Sports Nutrition, 16(1):56.
14Rao, T., Ozeki, M., & Juneja, L. (2015). In search of a safe natural sleep aid. Journal of the American College of Nutrition, 34(5):436-47.
15L-theanine side effects: top 10 potential adverse effects. Liftmode.com. Retrieved October 2, 2020 from https://liftmode.com/blog/l-theanine-side-effects/
16Caffeine. (n.d.). Wikipedia. Retrieved May 3, 2024 from https://en.wikipedia.org/wiki/Caffeine
17Temple, J., Bernard, C., Lipshultz, S., Czachor, J., Westphal, J., & Mestre, M. (2017). The safety of ingested caffeine: a comprehensive review. Frontiers In Psychiatry, 8:80.
18Rogers, P., Smith, J., Heatherley, S., & Pleydell-Pearce, C. (2008). Time for tea: mood, blood pressure and cognitive performance effects of caffeine and theanine administered alone and together. Psychopharmacology (Berlin), 195(4):569-77.
[This article was originally published on June 27, 2015. Updated May 3, 2024.]
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